Randomised clinical trial: transoral incisionless fundoplication vs. sham intervention to control chronic GERD
نویسندگان
چکیده
منابع مشابه
Transoral incisionless fundoplication: current status
PURPOSE OF REVIEW Transoral incisionless fundoplication (TIF) performed with the EsophyX device (Redmond, Washington, USA) is a totally endoscopic procedure with the objectives to mechanically repair a defective gastroesophageal valve and to reduce small hiatal hernias. The recent publication of randomized controlled trials and long-term follow-up data offers the opportunity to reevaluate this ...
متن کاملThe effects of transoral incisionless fundoplication on chronic GERD patients: 12-month prospective multicenter experience.
PURPOSE This study aimed to assess the impact of transoral incisionless fundoplication (TIF) on patients with chronic gastroesophageal reflux disease (GERD) at 12-month follow-up. METHODS Clinical outcomes of 100 consecutive patients with chronic GERD who underwent TIF between January 2010 and February 2011 were analyzed. RESULTS There were no major complications reported. Esophageal acid e...
متن کاملTransoral Incisionless Fundoplication Effective in Eliminating GERD Symptoms in Partial Responders to Proton Pump Inhibitor Therapy at 6 Months
BACKGROUND Incomplete control of troublesome regurgitation and extraesophageal manifestations of chronic gastroesophageal reflux disease (GERD) is a known limitation of proton pump inhibitor (PPI) therapy. This multicenter randomized study compared the efficacy of transoral incisionless fundoplication (TIF) against PPIs in controlling these symptoms in patients with small hiatal hernias. METH...
متن کاملReal-time measurement of luminal compliance during transoral incisionless fundoplication.
A 71-year-old woman who had a family history of esophageal cancer presented with symptoms of chronic heartburn. The patient expressed interest in definitive treatment, declining long-term medical therapy and opting to undergo transoral incisionless fundoplication (TIF) (●" Fig.1). This was accomplished by using the EsophyX Device (EndoGastric Solutions, San Mateo, California, USA). Before and a...
متن کاملEsophgeal Perforation and Bilateral Empyema Following Endoscopic EsophyX Transoral Incisionless Fundoplication
Transoral incisionless fundoplication (TIF) has been used for endoscopic treatment of gastroesophageal reflux disease (GERD). TIF using the EsophyX device system (EndoGastric Solutions) was designed to create a full-thickness valve at the gastroesophageal junction through the insertion of multiple fasteners; it improves GERD, reduces proton pump inhibitor use, and improves quality of life. Alth...
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ژورنال
عنوان ژورنال: Alimentary Pharmacology & Therapeutics
سال: 2015
ISSN: 0269-2813
DOI: 10.1111/apt.13427